Volume 12, Issue 3 (9-2024)                   JoMMID 2024, 12(3): 208-216 | Back to browse issues page

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Ibrahim M A, Doughari J H. Prevalence and Risk Factors of Hepatitis B and C Virus Co-Infection among Women Attending Antiretroviral Therapy Clinic in Yola, Nigeria. JoMMID 2024; 12 (3) :208-216
URL: http://jommid.pasteur.ac.ir/article-1-670-en.html
Prevalence and Risk Factors of Hepatitis B and C Virus Co-Infection among Women Attending Antiretroviral Therapy Clinic in Yola, Nigeria
Maryam Adam Ibrahim * , James Hamuel Doughari
College of Nursing and Midwifery, Department of Applied Sciences, PMB 2044, Yola, Nigeria.
Abstract:   (95 Views)
Introduction: Viral hepatitis represents a significant challenge to public health worldwide. Women living with HIV are at heightened risk of co-infection with hepatitis B and C due to their increased risk of exposure to bloodborne pathogens through medical interventions, potentially leading to severe health outcomes, including increased morbidity and mortality, and public health impacts through maternal transmission. This study aimed to estimate the prevalence of hepatitis B and C virus co-infection among women living with HIV attending the ART clinic in Modibbo Adama University Teaching Hospital, Yola, Nigeria. These findings will inform the development and improvement of testing, vaccination, and treatment programs to enhance health outcomes and quality of life for this population. Method: A cross-sectional study was conducted from January 2023 to September 2023 using a convenience sampling method to recruit 360 women aged 18 years and above attending the ART clinic. Data on socio-demographic characteristics and potential risk factors for HBV/HCV infection were collected with a structured questionnaire. The seroprevalence of HBsAg and anti-HCV antibodies was determined with Rapid Diagnostic Test (RDT) strips from Micropoint. Results: Among the 360 HIV-positive women tested, 9.2% (33) were co-infected with HBV, 2.2% (8) were co-infected with HCV, and 0.3% (1) had co-infection with HBV, HCV, and HIV. The prevalence of HBV co-infection was highest among women aged 39-48 (9.6%), while HCV co-infection was most prevalent in those aged 49 and above (3.4%). Logistic regression analysis showed that blood transfusion and having multiple sexual partners were significantly associated with HIV/HBV co-infection (P-value = 0.002). Conclusion: This study identified a notable prevalence of HBV (9.2%) and HCV (2.2%) co-infection among women living with HIV, underscoring the public health significance due to the potential for increased morbidity and mortality. Further studies should employ molecular techniques like PCR to confirm active infections and assess viral loads. This information is crucial for guiding treatment decisions and improving clinical outcomes for this vulnerable population.
Keywords: Co-infection, Hepatitis B virus, Hepatitis C virus, HIV infection, Nigeria, Risk factors, Women living with HIV
Full-Text [PDF 938 kb]   (39 Downloads)    
Type of Study: Original article | Subject: Infectious diseases and public health
Received: 2024/05/21 | Accepted: 2024/09/11 | Published: 2024/12/22
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.