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Omotola J, Ogbonna I, Iheukwumere C. Prevalence of Typhoidal Salmonella Infections and Associated Risk factors in Kaduna Metropolis, Nigeria. JoMMID 2020; 8 (3) :84-92
URL: http://jommid.pasteur.ac.ir/article-1-259-en.html
Prevalence of Typhoidal Salmonella Infections and Associated Risk factors in Kaduna Metropolis, Nigeria
Justina Omotola * , Innocent Ogbonna , Charles Iheukwumere
Federal University of Agriculture Makurdi Benue
Abstract:   (2610 Views)
Introduction: Salmonella species Salmonella typhi and Salmonella paratyphi, types A, B, and C are the causative agents of enteric fever. This disease continues to pose a severe threat to public health, especially in developing countries. This study investigated the prevalence of typhoidal Salmonella infections and the associated risk factors in Kaduna Metropolis, Nigeria. Methods: A questionnaire was used to obtain information from 250 patients attending four selected government hospitals and 50 healthy individuals as control. Blood samples from participants were obtained to determine the blood groups and genotypes, and stool specimens were used to isolate typhoidal Salmonella species. Results: Thirty cases were among symptomatic patients and two among controls showing a total prevalence of 10.6%. Among the 32 isolates, 25 were S. typhi (78.1%), and seven were S. paratyphi A (21.9%), revealing an approximate ratio of 4:1. Factors significantly associated with the infection prevalence included age, source of drinking water, and frequency of infection. Blood groups and genotypes were not statistically associated with the infection; however, individuals with blood group O and genotype AA were more commonly infected. Also, females, the age group 20-29, singles, and unemployed, showed more infections. Conclusion: The prevalence, the ratio of typhoidal Salmonella species, and the associated risk factors call for public health and control measures, including the provision of suitable drinking water and improving living and sanitary conditions.
Keywords: Typhoidal Salmonella, Enteric fever, Nigeria
Full-Text [PDF 1337 kb]   (1400 Downloads)    
Type of Study: Original article | Subject: Infectious diseases and public health
Received: 2020/07/19 | Accepted: 2020/07/20 | Published: 2020/12/26
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.