en Original article Original article <p> <strong> Introduction </strong><strong>: </strong>The decreased level of immunity in Human Immunodeficiency Virus (HIV) infected patients increases their vulnerability to various opportunistic fungal infections. Oral candidiasis has been found to be the most common fungal infection among HIV infected patients. The present study was conducted to evaluate the spectrum of various opportunistic fungal infections and their correlation with CD4+ counts. <strong>Methods: </strong>A total of 163 clinically suspected cases of fungal infections with HIV seropositive status were studied. <strong>Results: </strong>The most common infections observed were oropharyngeal candidiasis (39.26%) followed by cryptococcal meningitis (6.74%). The study showed opportunistic fungal infections in 46.6% of HIV infected patients with CD4+ counts ≤200 cell/ µl. <strong>Conclusion: </strong>Early diagnosis and prompt antifungal treatment is necessary to decrease the morbidity and mortality associated with the infections to increase the survival of HIV infected patients. <i>J Med Microbiol Infec Dis, 2014, 1 (2): 4 pages.</i> </p> Opportunistic Infections, HIV infection, Candida albicans, Cryptococcus neoformans 19 22 http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-25-15&slc_lang=en&sid=1 Sonali Jain No Department of Microbiology, Gold Field Institute of Medical Sciences and Research, Faridabad, Haryana, India Amit Kumar Singh Yes Department of Microbiology, Mayo Institute of Medical Sciences, Barabanki, Uttar Pradesh, India Ravinder Pal Singh No Department of Microbiology, Gold Field Institute of Medical Sciences and Research, Faridabad, Haryana, India Jyoti K Bajaj No Department of Microbiology, Government Medical College, Aurangabad, Maharashtra, India Ajit S Damle No Department of Microbiology, Government Medical College, Aurangabad, Maharashtra, India