Journal of Medical Microbiology and Infectious Diseases
Journal of Medical Microbiology and Infectious Diseases
JoMMID
Medical Sciences
http://jommid.pasteur.ac.ir
1
admin
2345-5349
2345-5330
8
10.61186/JoMMID
14
8888
13
en
jalali
1392
10
1
gregorian
2014
1
1
2
1
online
1
fulltext
en
Seroprevalence of Toxoplasma gondii Infection among Pregnant Women Admitted at Shahid Akbar Abadi Hospital, Tehran, Iran, 2010-2013
Original article
Original article
<p><strong>Introduction </strong><strong>: </strong>Toxoplasmosis, caused by <i>Toxoplasma gondii,</i> is a protozoan parasitic infection distributed worldwide. Early infection by this protozoa can lead to abortion and congenital toxoplasmosis in pregnant women. This study was conducted to determine the seroprevalence of <i>T. gondii</i> infection among pregnant women referring to Shahid Akbar Abadi Hospital, Tehran, Iran during 2010-2013. <strong>Methods: </strong>This descriptive study carried-out from October 2010 to March 2013. The blood samples from 785 pregnant women were collected and examined for specific IgG and IgM antibodies to <i>T. gondii</i> by ELISA method. <strong>Results: </strong>From 785 sera samples tested 541 (68.9%) were negative for any anti- <i>T. </i><i>gondii </i>antibody. The women with anti- <i>T. </i><i>gondii </i>positive and borderline IgG titers comprised 31.1% of the population study. <i>T. </i><i>gondii </i>specific IgM was negative for all the pregnant women examined, and only for 6 women the titer showed to be at borderline. The rate of infection increased with age, as the highest rate of seropositivity (42.2%) was observed in 35-50 age group. However, no significant difference in the seroprevalence of <i>T. </i><i>gondii </i>infection was observed between different age groups (<i>P </i>= 0.139). <strong>Conclusion: </strong>As a considerable number of the pregnant women were negative for <i>T. </i><i>gondii </i>antibodies and are prone to acquisition of acute <i>T. </i><i>gondii </i>infection over the course of pregnancy, primary prevention measures and serological monitoring of seronegative pregnant women are important for preventing congenital toxoplasmosis. <i>J Med Microbiol Infec Dis, 2014, 1 (2): 4 pages. </i></p>
Toxoplasma gondii, Pregnant Women, Seroprevalence
16
18
http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-42-1&slc_lang=en&sid=1
Hadi
Ghasemloo
1003194753284600550
1003194753284600550
No
Shahid Akbar Abadi Hospital, Tehran University of Medical Sciences, Tehran, Iran
Mohsen
Ghomashlooyan
1003194753284600551
1003194753284600551
No
Department of Laboratory Medicine, School of Paramedicine, Kashan University of Medical Sciences, Kashan, Iran
Hossein
Hooshyar
1003194753284600552
1003194753284600552
Yes
Anatomical Science Research Center, Kashan University of Medical Sciences, Kashan, Iran