TY - JOUR T1 - Effects of Extracts and an Essential Oil from Some Medicinal Plants against Biofilm Formation of Pseudomonas aeruginosa TT - JF - JoMMID JO - JoMMID VL - 1 IS - 1 UR - http://jommid.pasteur.ac.ir/article-1-38-en.html Y1 - 2013 SP - 36 EP - 40 KW - Pseudomonas aeruginosa KW - Biofilm KW - Plant extract KW - Drug resistance N2 -   Biofilm of Pseudomonas aeruginosa, an opportunistic pathogen, can cause serious health problems, such as chronic infections, especially in immunocompromised patients. Many studies have suggested administration of new generation of antibiotics, as P. aeruginosa biofilms have developed high resistance to antimicrobial drugs. This study reports the inhibitory effect of three medicinal plant extracts and an essential oil on biofilm formation by a clinical isolate of P. aeruginosa. In this study biofilm formation of P. aeruginosa strain 214 was determined in presence of three plant extracts, Cyclamen coum, Dianthus orieltalis and Origanum majorana, and Zataria multiflora Bio essential oil. Minimum Biofilm Inhibitory Concentrations (MBICs) were determined by microdilution techniques and XTT assay. The C. coam extract and Z. multiflora Bio essential oil inhibited biofilm formation completely at concentrations M3 ER -