Volume 3, Issue 3 And 4 (7-2015)                   JoMMID 2015, 3(3 And 4): 71-74 | Back to browse issues page

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Mobaiyen H, Nasarollah Pour M, Elmi F. Phytochemical Composition and Antibacterial Activity of Trachyspermum copticum L. essential oil, East Azerbaijan, Iran. JoMMID. 2015; 3 (3 and 4) :71-74
URL: http://jommid.pasteur.ac.ir/article-1-103-en.html
Department of Microbiology, Tabriz branch, Islamic Azad University, Tabriz, Iran.
Abstract:   (3955 Views)

Introduction: The aim of this study was to characterize the chemical composition and antimicrobial activity of Trachyspermum copticum essential oil (EO). Methods: The chemical composition of seed samples obtained from Mianeh city in East Azerbaijan, was assessed using gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity was evaluated by disc diffusion method against methicillin-resistant Staphylococcus aureus (MRSA), other extended-spectrum beta-lactamases (ESBLs) producing, as well as Gram-negative and Gram-positive bacteria. The minimum inhibitory concentration (MIC) value of EO was assessed using agar dilution method. Results: Thirteen monoterpene hydrocarbons (57.6%) and oxygenated monoterpenes (42.4%) compounds were identified in the EO, of which, 3 compounds, including thymol, m-cymene, and, γ-terpinene were the major components of the EO with quantities of 41.9, 33.53, and 20.42%, respectively. The EO showed antimicrobial activity against ten microorganisms, especially Streptococcus sanguis, S. aureus (MRSA strain), and Klebsiella pneumoniae (ESBL-producing strain), which was potentially better than tetracycline and kanamycin. Conclusion: This study confirmed that EO of T. copticum has in vitro antimicrobial activity against Gram-negative and Gram-positive bacteria, which has made it an alternative antibacterial agent.

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Type of Study: Original article | Subject: Other
Received: 2016/09/11 | Accepted: 2017/04/24 | Published: 2017/05/22

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