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Khakifirouz S, Mowla S J, Baniasadi V, Fazlalipour M, Jalali T, Mirghiasi S M et al . No Detection of Crimean Congo Hemorrhagic Fever (CCHF) Virus in Ticks from Kerman Province of Iran. JoMMID 2018; 6 (4) :108-111
URL: http://jommid.pasteur.ac.ir/article-1-187-en.html
No Detection of Crimean Congo Hemorrhagic Fever (CCHF) Virus in Ticks from Kerman Province of Iran
Sahar Khakifirouz , Seyed Javad Mowla , Vahid Baniasadi , Mehdi Fazlalipour , Tahmineh Jalali , Seyedeh Maryam Mirghiasi , Mostafa Salehi-Vaziri
Department of Arboviruses and Viral Hemorrhagic Fevers (National Ref. Lab), Pasteur Institute of Iran
Abstract:   (4331 Views)
Introduction: Crimean Congo Hemorrhagic Fever (CCHF) is a fatal tick-borne viral zoonosis with a case fatality rate of 5% to 30%. CCHF has been documented as the most frequent tick-borne viral infection in Iran with more than 50 cases annually. Kerman Province in the south of Iran is one of the CCHF-endemic areas of the country, but no data on infection of ticks with this virus from this area is available. This study aimed to investigate the CCHFV infection among ticks collected from 4 different counties in this province. Methods: In 2011, a total of 203 hard ticks were collected from Kerman, Jiroft, Sirjan, and Kuhbanan counties in Kerman Province, southeast of Iran. Infection of ticks with CCHFV was investigated using RT-PCR targeting the small segment of the viral genome. Results: Out of 203 ticks, Dermacentor (50.24%) was the most frequent genus followed by Hyalomma (39.39%), Haemaphysalis (9.85%) and Rhipicephalus (0.49%). Our results showed no CCHFV infection of ticks. Conclusion: Our finding indicates no circulation of CCHFV in ticks from Kerman Province. However, as Kerman Province is an endemic region for CCHF, further investigations are needed to have a better understanding of the CCHFV vectors in this region.
Keywords: Crimean Congo Hemorrhagic Fever, Tick-Borne Diseases, Ixodidae, Iran
Full-Text [PDF 265 kb]   (2264 Downloads)    
Type of Study: Original article |
Received: 2019/03/3 | Accepted: 2019/04/28 | Published: 2019/07/3
References
1. 1. Maes P, Alkhovsky SV, Bào Y, Beer M, Birkhead M, Briese T, et al. Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018. Arch Virol. 2018; 163 (8): 2295-310. [DOI:10.1007/s00705-018-3843-5]
2. Spengler JR, Bergeron É, Spiropoulou CF. Crimean-Congo hemorrhagic fever and expansion from endemic regions. Curr Opin Virol. 2019; 34: 70-8. [DOI:10.1016/j.coviro.2018.12.002]
3. Blair PW, Kuhn JH, Pecor DB, Apanaskevich DA, Kortepeter MG, Cardile AP, et al. An emerging biothreat: Crimean-Congo hemorrhagic fever virus in southern and western Asia. Am J Trop Med Hyg. 2019; 100 (1): 16-23. [DOI:10.4269/ajtmh.18-0553]
4. Bente DA, Forrester NL, Watts DM, McAuley AJ, Whitehouse CA, Bray M. Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity. Antiv Res. 2013; 100 (1): 159-89. [DOI:10.1016/j.antiviral.2013.07.006]
5. Gargili A, Thangamani S, Bente DA. Influence of laboratory animal hosts on the life cycle of Hyalomma marginatum and implications for an in vivo transmission model for Crimean-Congo hemorrhagic fever virus. Front Cell Infect Microb. 2013; 3: 39. [DOI:10.3389/fcimb.2013.00039]
6. Hoogstraal H. The epidemiology of tick-borne Crimean-Congo hemorrhagic fever in Asia, Europe, and Africa. J Med Entomol. 1979; 15 (4): 307-417. [DOI:10.1093/jmedent/15.4.307]
7. Ahmadkhani M, Alesheikh AA, Khakifirouz S, Salehi-Vaziri M. Space-time epidemiology of Crimean-Congo hemorrhagic fever (CCHF) in Iran. Ticks Tick-Borne Dis. 2018; 9 (2): 207-16. [DOI:10.1016/j.ttbdis.2017.09.006]
8. Mostafavi E, Haghdoost A, Khakifirouz S, Chinikar S. Spatial analysis of Crimean Congo hemorrhagic fever in Iran. Am J Trop Med Hyg. 2013; 89 (6): 1135-41. [DOI:10.4269/ajtmh.12-0509]
9. Champour M, Chinikar S, Mohammadi G, Razmi G, Shah-Hosseini N, Khakifirouz S, et al. Molecular epidemiology of Crimean-Congo hemorrhagic fever virus detected from ticks of one humped camels (Camelus dromedarius) population in northeastern Iran. J Parasit Dis. 2016; 40 (1): 110-5. [DOI:10.1007/s12639-014-0458-y]
10. Kayedi MH, Chinikar S, Mostafavi E, Khakifirouz S, Jalali T, Hosseini-Chegeni A, et al. Crimean-Congo hemorrhagic fever virus clade iv (Asia 1) in ticks of western Iran. J Med Entomol. 2015; 52 (5): 1144-9. [DOI:10.1093/jme/tjv081]
11. Estrada-Pena A, Bouattour A, Camicas J, Walker A. Ticks of domestic animals in the Mediterranean region. University of Zaragoza, Spain. 2004; 131.
12. Fazlalipour M, Baniasadi V, Mirghiasi SM, Jalali T, Khakifirouz S, Azad-Manjiri S, et al. Crimean-Congo hemorrhagic fever due to consumption of raw meat: a case reports from East-North of Iran. Jpn J Infect Dis. 2016: JJID. 2015.498. [DOI:10.7883/yoken.JJID.2015.498]
13. Mehravaran A, Moradi M, Telmadarraiy Z, Mostafavi E, Moradi AR, Khakifirouz S, et al. Molecular detection of Crimean-Congo haemorrhagic fever (CCHF) virus in ticks from southeastern Iran. Ticks Tick-Borne Dis. 2013; 4 (1-2): 35-8. [DOI:10.1016/j.ttbdis.2012.06.006]
14. Yaser SA, Sadegh C, Zakkyeh T, Hassan V, Maryam M, Ali OM, et al. Crimean-Congo hemorrhagic fever: a molecular survey on hard ticks (Ixodidae) in Yazd province, Iran. Asian Pac J Trop Med. 2011; 4 (1): 61-3. [DOI:10.1016/S1995-7645(11)60034-5]
15. Tahmasebi F, Ghiasi SM, Mostafavi E, Moradi M, Piazak N, Mozafari A, et al. Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran. J Vector Dis. 2010; 47 (4): 211-7.
16. Telmadarraiy Z, Ghiasi SM, Moradi M, Vatandoost H, Eshraghian MR, Faghihi F, et al. A survey of Crimean-Congo haemorrhagic fever in livestock and ticks in Ardabil Province, Iran during 2004-2005. Scand J Infect Dis. 2010; 42 (2): 137-41. [DOI:10.3109/00365540903362501]
17. Salehi-Vaziri M, Baniasadi V, Jalali T, Mirghiasi SM, Azad-Manjiri S, Zarandi R, et al. The first fatal case of Crimean-Congo hemorrhagic fever caused by the AP92-like strain of the Crimean-Congo hemorrhagic fever virus. Jpn J Infect Dis. 2016; 69 (4): 344-6. [DOI:10.7883/yoken.JJID.2015.533]
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Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.